兔抗ITGB2多克隆抗體

Background:

The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Applications:

ELISA, IHC

Name of antibody:

ITGB2

Immunogen:

Fusion protein of human ITGB2

Full name:

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

Synonyms：

LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1

SwissProt:

P05107

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human brain

IHC Recommend dilution:

25-100