兔抗ADD1多克隆抗體

Background:

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Applications:

ELISA, IHC

Name of antibody:

ADD1

Immunogen:

Fusion protein of human ADD1

Full name:

Alpha-adducin

Synonyms：

ADDA

SwissProt:

P35611

ELISA Recommended dilution:

500-5000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

50-200