兔抗ADAM17(Phospho-Thr735) 多克隆抗體

Background:

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.

Applications:

WB

Name of antibody:

ADAM17(Phospho-Thr735)

Immunogen:

Peptide sequence around phosphorylation site of Threonine 735 (P-Q-T(p)-P-G) derived from Human ADAM 17.

Full name:

ADAM metallopeptidase domain 17

Synonyms：

CSVP; TACE; NISBD; ADAM18; CD156B

SwissProt:

P78536

WB Predicted band size:

93 kDa

WB Positive control:

K562 cells lysates treated with UV

WB Recommended dilution:

500-1000