兔抗LIFR多克隆抗體

Background:

This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

LIFR

Immunogen:

Synthetic peptide of human LIFR

Full name:

leukemia inhibitory factor receptor alpha

Synonyms：

SWS, SJS2, STWS, CD118, LIF-R

SwissProt:

P42702

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer and Human ovarian cancer

IHC Recommend dilution:

25-100