兔抗LRRC15多克隆抗體

Background:

Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer’s disease.

Applications:

ELISA, IHC

Name of antibody:

LRRC15

Immunogen:

Fusion protein of human LRRC15

Full name:

leucine rich repeat containing 15

Synonyms：

LIB

SwissProt:

Q8TF66

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human prostate cancer and Human cervical cancer

IHC Recommend dilution:

100-300