小鼠抗RIOK2單克隆抗體

Background:

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. RIOK2 (RIO kinase 2) is a 552 amino acid protein that contains one protein kinase domain and belongs to the RIO subfamily of atypical Ser/Thr protein kinases. RIOK2 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play an important role in ribosome biogenesis and cell cycle progression.

Applications:

WB, IHC, IF

Name of antibody:

RIOK2

Immunogen:

Fusion protein of human RIOK2

Full name:

RIO kinase 2 (RIOK2), transcript variant 1

Synonyms:

RIO2

SwissProt:

Q9BVS4

IHC positive control:

adenocarcinoma of human ovary tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

63 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MCF-7 cell lysates

WB Recommended dilution:

500-2000