小鼠抗SDCBP單克隆抗體

Background:

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Applications:

WB, IHC

Name of antibody:

SDCBP

Immunogen:

Fusion protein of human SDCBP

Full name:

syndecan binding protein (syntenin) (SDCBP), transcript variant 1

Synonyms:

MDA-9; MDA9; ST1; SYCL; TACIP18

SwissProt:

O00560

IHC positive control:

adenocarcinoma of human ovary tissue and adenocarcinoma of human endometrium tissue; human liver tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

32 kDa

WB Positive control:

HepG2, Hela, A549, Jurkat, MCF-7 cell lysates

WB Recommended dilution:

500-2000