兔抗CIRBP多克隆抗體

Background:

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Applications:

ELISA, IHC

Name of antibody:

CIRBP

Immunogen:

Full length fusion protein

Full name:

cold inducible RNA binding protein

Synonyms:

CIRP

SwissProt:

Q14011

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer;Human tonsil

IHC Recommend dilution:

20-100