兔抗CLDN1多克隆抗體

Background:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Applications:

ELISA, WB, IHC

Name of antibody:

CLDN1

Immunogen:

Synthetic peptide of human CLDN1

Full name:

claudin 1

Synonyms：

CLD1, SEMP1, ILVASC

SwissProt:

O95832

ELISA Recommended dilution:

1000-10000

IHC positive control:

Human esophagus cancer and Human cervical cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

23 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

1000-3000