兔抗CRKL多克隆抗體

Background:

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Applications:

ELISA, WB, IHC

Name of antibody:

CRKL

Immunogen:

Synthetic peptide of human CRKL

Full name:

v-crk avian sarcoma virus CT10 oncogene homolog-like

SwissProt:

P46109

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

34 kDa

WB Positive control:

Lovo, A431, A549, hela, hepG2 and Raji cells, mouse brain tissue

WB Recommended dilution:

500-2000