中文名稱:AMHR2 抗原(重組蛋白)
英文名稱: AMHR2 Antigen (Recombinant Protein)
別 名: anti-Mullerian hormone receptor, type II; AMHR; MRII; MISR2; MISRII
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 203-518 amino acids of human AMHR2 |
Full name: |
anti-Mullerian hormone receptor, type II |
Synonyms: |
AMHR; MRII; MISR2; MISRII |
Swissprot: |
Q16671 |
Gene Accession: |
BC126316 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. |