中文名稱(chēng):APLF 抗原(重組蛋白)
英文名稱(chēng): APLF Antigen (Recombinant Protein)
別 名: aprataxin and PNKP like factor; APFL; PALF; Xip1; C2orf13
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human APLF |
Full name: |
aprataxin and PNKP like factor |
Synonyms: |
APFL; PALF; Xip1; C2orf13 |
Swissprot: |
Q8IW19 |
Gene Accession: |
BC041144 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. |