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  • ATF6B抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16205
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:40
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中文名稱(chēng): ATF6B抗原(重組蛋白)

英文名稱(chēng): ATF6B Antigen (Recombinant Protein)

別       名: activating transcription factor 6 beta; G13; CREBL1; CREB-RP

儲(chǔ)       存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概述

Fusion protein corresponding to a region derived from 2-200 amino acids of human ATF6B

技術(shù)規(guī)格

Full name:

activating transcription factor 6 beta

Synonyms:

G13; CREBL1; CREB-RP

Swissprot:

Q99941

Gene Accession:

BC008394

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.