兔抗CTNNB1(phospho-Tyr333) 多克隆抗體

Background:

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.

Applications:

WB, IHC

Name of antibody:

CTNNB1(phospho-Tyr333)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 333 (Y-T-Y(p)-E-K) derived from Human β-catenin

Full name:

catenin (cadherin-associated protein), beta 1, 88kDa

Synonyms：

CTNNB; MRD19; armadillo

SwissProt:

P35222

IHC positive control:

Human lung carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

85 kDa

WB Positive control:

293 cells lysates untreated or treated with FSK

WB Recommended dilution:

500-1000