HPGD抗原（重組蛋白）

Full name:

hydroxyprostaglandin dehydrogenase 15-(NAD)

Synonyms:

PGDH; PGDH1; PHOAR1; 15-PGDH; SDR36C1

Swissprot:

P15428

Gene Accession:

BC018986

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.