中文名稱(chēng): EZR抗原(重組蛋白)
英文名稱(chēng): EZR Antigen (Recombinant Protein)
別 名: CVL; CVIL; VIL2; HEL-S-105
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to a region derived from 2-295 amino acids of human EZR |
Full name: |
ezrin |
Synonyms: |
CVL; CVIL; VIL2; HEL-S-105 |
Swissprot: |
P15311 |
Gene Accession: |
BC013903 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |