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  • HSD11B1抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17425
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱：  HSD11B1抗原（重組蛋白）

英文名稱： HSD11B1 Antigen (Recombinant Protein)

別      名： HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1

儲      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概  述：

Fusion protein corresponding to a region derived from 25-292 amino acids of human HSD11B1


技術(shù)規(guī)格：

Full name:

hydroxysteroid 11-beta dehydrogenase 1

Synonyms:

HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1

Swissprot:

P28845

Gene Accession:

BC012593

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.