兔抗DDX54多克隆抗體

Background:

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

DDX54

Immunogen:

Fusion protein of human DDX54

Full name:

DEAD-box helicase 54

Synonyms:

DP97

SwissProt:

Q8TDD1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

99 kDa

WB Positive control:

293T, A549 and HEPG2 cell lysates

WB Recommended dilution:

200-1000