ITLN1 抗原（重組蛋白）

Full name:

intelectin 1 (galactofuranose binding)

Synonyms:

HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin

Swissprot:

Q8WWA0

Gene Accession:

BC020664

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Intelectin-1 also known as the intestinal lactoferrin receptor is a protein that in humans is encoded by the ITLN1 gene.Intelectin-1 functions both as a receptor for bacterial arabinogalactans and for lactoferrin. Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner.