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  • 兔抗MCAM多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18155
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱:  兔抗MCAM多克隆抗體


英文名稱:  Anti-MCAM rabbit polyclonal antibody


別       名:  CD146, MUC18


相關(guān)類別:  一抗


儲      存:  冷凍(-20℃)


宿      主:  Rabbit


抗      原:  MCAM


反應(yīng)種屬:  Human


標 記  物:  Unconjugate


克隆類型:  rabbit polyclonal


技術(shù)規(guī)格

Background:

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Applications:

ELISA, WB, IHC

Name of antibody:

MCAM

Immunogen:

Synthetic peptide of human MCAM

Full name:

melanoma cell adhesion molecule

Synonyms:

CD146; MUC18; HEMCAM; METCAM; MelCAM

SwissProt:

P43121

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human ovarian cancer

IHC Recommend dilution:

40-200

WB Predicted band size:

72 kDa

WB Positive control:

Human leiomyosarcoma tissue lysate

WB Recommended dilution:

500-2000