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  • LILRB1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18245
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱LILRB1抗原(重組蛋白)

英文名稱 LILRB1 Antigen (Recombinant Protein)

別      名: ILT2; LIR1; MIR7; CD85J; ILT-2; LIR-1; MIR-7

儲      存 冷凍(-20℃)

相關(guān)類別: 抗原

概      述

Fusion protein corresponding to a region derived from 453-650 amino acids of human LILRB1


技術(shù)規(guī)格

Full name:

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1

Synonyms:

ILT2; LIR1; MIR7; CD85J; ILT-2; LIR-1; MIR-7

Swissprot:

Q8NHL6

Gene Accession:

BC015731

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.