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  • NTAN1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18316
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱:NTAN1抗原(重組蛋白)

英文名稱: NTAN1 Antigen (Recombinant Protein)

別      名: PNAA; PNAD

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概      述:

Fusion protein corresponding to a region derived from 1-310 amino acids of human NTAN1


技術(shù)規(guī)格:

Full name:

N-terminal asparagine amidase

Synonyms:

PNAA; PNAD

Swissprot:

Q96AB6

Gene Accession:

BC017336

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.