ST8SIA4抗原（重組蛋白）

Full name:

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

Synonyms:

PST; PST1; SIAT8D; ST8SIA-IV

Swissprot:

Q92187

Gene Accession:

BC027866

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.