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  • ATP6V1C1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18544
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱(chēng):ATP6V1C1抗原(重組蛋白)

英文名稱(chēng): ATP6V1C1 Antigen (Recombinant Protein)

別      名: VATC; Vma5; ATP6C; ATP6D

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概      述:

Fusion protein corresponding to a region derived from 183-382 amino acids of human ATP6V1C1


技術(shù)規(guī)格:

Full name:

ATPase H+ transporting V1 subunit C1

Synonyms:

VATC; Vma5; ATP6C; ATP6D

Swissprot:

P21283

Gene Accession:

BC010960

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.