兔抗DNM2多克隆抗體

Background:

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

DNM2

Immunogen:

Synthetic peptide of human DNM2

Full name:

dynamin 2

Synonyms：

DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB

SwissProt:

P50570

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human gastric cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

98 kDa

WB Positive control:

Raji cells and human fetal liver tissue, NIH/3T3 cells and mouse brain tissue, hela cells

WB Recommended dilution:

500-2000