兔抗DVL1多克隆抗體

Background:

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Applications:

ELISA, IHC

Name of antibody:

DVL1

Immunogen:

Synthetic peptide of human DVL1

Full name:

dishevelled segment polarity protein 1

Synonyms：

DVL; DRS2; DVL1L1; DVL1P1

SwissProt:

O14640

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100