中文名稱(chēng): 兔抗MLANA多克隆抗體
英文名稱(chēng): Anti-MLANA rabbit polyclonal antibody
別 名: MART1; MART-1
相關(guān)類(lèi)別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: MLANA
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類(lèi)型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Melan-A (also designated MART-1) is a melanocyte differentiation antigen that is specific to melanomas, melanocyte cell lines and retina. Melan-A peptide is recognized by most HLA-A2-restricted tumor-specific tumor-infiltrating lymphocytes in patients with melanoma. Antimelanoma cytotoxic T lymphocytes can be generated with a Melan-A peptide, implicating Melan-A as a potential candidate for antigen-specific immunotherapy in melanoma patients. Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. |
Applications: |
ELISA, IHC |
Name of antibody: |
MLANA |
Immunogen: |
Synthetic peptide of human MLANA |
Full name: |
melan-A |
Synonyms: |
MART1; MART-1 |
SwissProt: |
Q16655 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer |
IHC Recommend dilution: |
40-250 |