兔抗GTF3A多克隆抗體

Background:

The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.

Applications:

ELISA, IHC

Name of antibody:

GTF3A

Immunogen:

Synthetic peptide of human GTF3A

Full name:

general transcription factor IIIA

Synonyms:

AP2; TFIIIA

SwissProt:

Q92664

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

50-300