兔抗MRPL12多克隆抗體

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.

Applications:

ELISA, WB, IHC

Name of antibody:

MRPL12

Immunogen:

Fusion protein of human MRPL12

Full name:

mitochondrial ribosomal protein L12

Synonyms：

5c5-2; L12mt; MRPL7; RPML12; MRPL7/L12; MRP-L31/34

SwissProt:

P52815

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human cervical cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

21 kDa

WB Positive control:

293T cells

WB Recommended dilution:

500-2000