儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Full name: |
NME/NM23 nucleoside diphosphate kinase 6 |
Synonyms: |
NDK 6; NM23-H6; IPIA-ALPHA |
Swissprot: |
O75414 |
Gene Accession: |
BC001808 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis. |