英文名稱: NDUFA2 Antigen (Recombinant Protein)
相關類別: 抗原
概 述
Full name: |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
Synonyms: |
B8; CD14; CIB8 |
Swissprot: |
O43678 |
Gene Accession: |
BC003674 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. |