兔抗EPHB4多克隆抗體

Background:

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Applications:

ELISA, IHC

Name of antibody:

EPHB4

Immunogen:

Synthetic peptide of human EPHB4

Full name:

EPH receptor B4

Synonyms：

HTK; MYK1; TYRO11

SwissProt:

P54760

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and Human thyroid cancer

IHC Recommend dilution:

25-100