兔抗ESRP2多克隆抗體

Background:

mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Applications:

ELISA, WB, IHC

Name of antibody:

ESRP2

Immunogen:

Synthetic peptide of human ESRP2

Full name:

epithelial splicing regulatory protein 2

Synonyms:

RBM35B

SwissProt:

Q9H6T0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and Human thyroid cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

78 kDa

WB Positive control:

Human bladder transitional cell carcinoma grade 2-3 tissue lysate

WB Recommended dilution:

200-1000