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021-54845833/15800441009
中文名稱： 兔抗MYSM1多克隆抗體
英文名稱： Anti-MYSM1 rabbit polyclonal antibody
別 名： 2ADUB, 2A-DUB, RP4-592A1.1
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MYSM1
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MYSM1 |
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Immunogen: |
Synthetic peptide of human MYSM1 |
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Full name: |
Myb-like, SWIRM and MPN domains 1 |
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Synonyms： |
2ADUB, 2A-DUB, RP4-592A1.1 |
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SwissProt: |
Q5VVJ2 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human ovarian cancer |
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IHC Recommend dilution: |
50-200 |
