兔抗RPS6KA1 (Phospho-Thr348)多克隆抗體

Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.

Applications:

WB, IHC, IF

Name of antibody:

RPS6KA1 (Phospho-Thr348)

Immunogen:

Synthetic peptide of human RPS6KA1 (Phospho-Thr348)

Full name:

ribosomal protein S6 kinase, 90kDa, polypeptide 1 (Phospho-Thr348)

Synonyms：

RSK; HU-1; RSK1; MAPKAPK1A

SwissProt:

Q15418

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

90 kDa

WB Positive control:

Hela cells untreated or treated with UV

WB Recommended dilution:

500-1000

IF Positive control:

Hela cells

IF Recommended dilution

100-200