兔抗RPS6KB1(Phospho-Thr389/412) 多克隆抗體

Background:

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations.

Applications:

WB

Name of antibody:

RPS6KB1(Phospho-Thr389/412)

Immunogen:

Peptide sequence around phosphorylation site of threonine389/412(G-F-T(p)-Y-V) derived from Human p70 S6 Kinase .

Full name:

ribosomal protein S6 kinase, 70kDa, polypeptide 1

Synonyms：

S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha

SwissProt:

P23443

WB Predicted band size:

59 kDa

WB Positive control:

Jurkat cells lysates treated with Insulin

WB Recommended dilution:

500-1000