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  • 兔抗SF3B3多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW21051
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
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中文名稱:  兔抗SF3B3多克隆抗體  

英文名稱: Anti-SF3B3 rabbit polyclonal antibody

別    名: splicing factor 3b subunit 3; RSE1; SAP130; SF3b130; STAF130

相關(guān)類別: 一抗

儲(chǔ)    存: 冷凍(-20℃)

宿    主: Rabbit

抗    原: SF3B3

反應(yīng)種屬: Human, Mouse

標(biāo) 記 物 Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

Applications:

ELISA, IHC

Name of antibody:

SF3B3

Immunogen:

Fusion protein of human SF3B3

Full name:

splicing factor 3b subunit 3

Synonyms:

RSE1; SAP130; SF3b130; STAF130

SwissProt:

Q15393

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human thyroid cancer

IHC Recommend dilution:

50-300