中文名稱: 兔抗PAPPA-AS1多克隆抗體
英文名稱: Anti-PAPPA-AS1 rabbit polyclonal antibody
別 名: DIPAS; TAF4B; PAPPAS; TAF2C2; PAPPAAS; PAPPA-AS; TAFII105; NCRNA00156
相關(guān)類別: 一抗
抗 原: PAPPA-AS1
儲 存: 冷凍(-20℃)
宿 主: Rabbit
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
PAPP A was originally isolated from pregnancy serum as heterotetrameric protein complex with molecular weight approximately 500 kDa, consisting of two PAPP A subunits disulfide-linked with two subunits of the proform of eosinophil major basic protein (proMBP). In such a complex proMBP functions as an inhibitor of PAPP A proteinase activity. PAPP A is widely used as a marker of some pathologies during pregnancy. Reduced level of PAPP A in pregnancy blood in the first trimester is associated with fetal Down syndrome. PAPP A is considered as one of the best biochemical markers in early pregnancy used to screen for Down syndrome during the first trimester (Wald, N. J. et al). |
Applications: |
ELISA, IHC |
Name of antibody: |
PAPPA-AS1 |
Immunogen: |
Synthetic peptide of human PAPPA-AS1 |
Full name: |
PAPPA antisense RNA 1 |
Synonyms: |
DIPAS; TAF4B; PAPPAS; TAF2C2; PAPPAAS; PAPPA-AS; TAFII105; NCRNA00156 |
SwissProt: |
Q5QFB9 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
20-100 |