兔抗GP6多克隆抗體

Background:

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

GP6

Immunogen:

Synthetic peptide of human GP6

Full name:

glycoprotein VI platelet

Synonyms:

GPIV; GPVI; BDPLT11

SwissProt:

Q9HCN6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human thyroid cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

37 kDa

WB Positive control:

K562,Jurkat and 293T cell lysates

WB Recommended dilution:

200-1000