兔抗PPM1B多克隆抗體

Background:

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Applications:

ELISA, IHC

Name of antibody:

PPM1B

Immunogen:

Fusion protein of human PPM1B

Full name:

protein phosphatase, Mg2+/Mn2+ dependent 1B

Synonyms:

PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X

SwissProt:

O75688

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

50-300