兔抗GRB10多克隆抗體

Background:

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications:

ELISA, IHC

Name of antibody:

GRB10

Immunogen:

Synthetic peptide of human GRB10

Full name:

growth factor receptor-bound protein 10

Synonyms：

RSS, IRBP, MEG1, GRB-IR, Grb-10

SwissProt:

Q13322

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human tonsil

IHC Recommend dilution:

10-50