兔抗SPDL1多克隆抗體

Background:

Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.

Applications:

ELISA, IHC

Name of antibody:

SPDL1

Immunogen:

Synthetic peptide of humanSPDL1

Full name:

spindle apparatus coiled-coil protein 1

Synonyms：

CCDC99

SwissProt:

Q96EA4

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human esophagus cancer

IHC Recommend dilution:

25-100