兔抗VASP (Phospho-Ser157)多克隆抗體

Background:

Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.

Applications:

WB, IHC

Name of antibody:

VASP (Phospho-Ser157)

Immunogen:

Synthetic peptide of human VASP (Phospho-Ser157)

Full name:

vasodilator-stimulated phosphoprotein (Phospho-Ser157)

SwissProt:

P50552

IHC positive control:

Human tonsil carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

40 kDa

WB Positive control:

C6 cells treated with PMA

WB Recommended dilution:

500-1000