兔抗VAV1(Ab-174) 多克隆抗體

Background:

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1.

Applications:

WB

Name of antibody:

VAV1(Ab-174)

Immunogen:

Synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).

Full name:

vav 1 guanine nucleotide exchange factor

Synonyms：

VAV

SwissProt:

P15498

WB Predicted band size:

98 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000