兔抗ATG4C多克隆抗體

Background:

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

Applications:

ELISA, WB, IHC

Name of antibody:

ATG4C

Immunogen:

Fusion protein of human ATG4C

Full name:

autophagy related 4C, cysteine peptidase

Synonyms：

APG4C; AUTL1; AUTL3; APG4-C

SwissProt:

Q96DT6

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human brain and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

52 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

200-1000