兔抗BRAF多克隆抗體

Background:

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

BRAF

Immunogen:

Synthetic peptide of human BRAF

Full name:

v-raf murine sarcoma viral oncogene homolog B

Synonyms：

NS7; BRAF1; RAFB1; B-RAF1

SwissProt:

P15056

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and Human prostate cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

84 kDa

WB Positive control:

Hela and Raji cells

WB Recommended dilution:

500-2000