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  • 兔抗CBL (phospho-Tyr700)多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW4393
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中文名稱:兔抗CBL (phospho-Tyr700)多克隆抗體

英文名稱: Anti-CBL (phospho-Tyr700) rabbit polyclonal antibody

別      名: CBL2; NSLL; C-CBL; RNF55; FRA11B

相關(guān)類別: 一抗

儲      存: 冷凍(-20℃) 避光

宿      主: Rabbit

抗      原:
CBL (phospho-Tyr700)

反應(yīng)種屬: Human, Mouse, Rat

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.

Applications:

WB, IHC, IF

Name of antibody:

CBL (phospho-Tyr700)

Immunogen:

Synthetic peptide of human CBL (phospho-Tyr700)

Full name:

Cbl proto-oncogene, E3 ubiquitin protein ligase (phospho-Tyr700)

Synonyms:

CBL2; NSLL; C-CBL; RNF55; FRA11B

SwissProt:

P22681

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

120 kDa

WB Positive control:

HT29 cells treated with UV

WB Recommended dilution:

500-1000

IF Positive control:

Hela cells

IF Recommended dilution

100-200