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  • 兔抗CCDC134多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW4517
    • 應(yīng)用 : 僅用于科研使用
    • 保存條件 : 低溫保存
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中文名稱:兔抗CCDC134多克隆抗體   

英文名稱:
Anti-CCDC134 rabbit polyclonal antibody

別      名: coiled-coil domain containing 134

相關(guān)類(lèi)別: 一抗

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: CCDC134

反應(yīng)種屬: Human, Mouse, Rat

標(biāo) 記 物: Unconjugate

克隆類(lèi)型: rabbit polyclonal

技術(shù)規(guī)格

Background:

In extracellular secreted form, promotes proliferation and activation of CD8+ T cells, suggesting a cytokine-like function (PubMed:25125657). Enhances cytotoxic anti-tumor activity of CD8+ T cells (PubMed:25125657). May inhibit ERK and JNK signaling activity (PubMed:18087676, PubMed:23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed:23070808). In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF-mediated H3K14 and H4K8 HAT activity. May inhibit TADA2A-mediated TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote TADA2A-mediated XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.

Applications:

ELISA, WB, IHC

Name of antibody:

CCDC134

Immunogen:

Fusion protein of human CCDC134

Full name:

coiled-coil domain containing 134

SwissProt:

Q9H6E4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

27 kDa

WB Positive control:

Human fetal liver tissue, 293T cell lysates

WB Recommended dilution:

1000-5000