兔抗XIAP(Phospho-Ser87) 多克隆抗體

Background:

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme.

Applications:

WB

Name of antibody:

XIAP(Phospho-Ser87)

Immunogen:

Peptide sequence around phosphorylation site of serine87(K-V-S(p)-P-N) derived from Human XIAP .

Full name:

X-linked inhibitor of apoptosis

Synonyms：

API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3

SwissProt:

P98170

WB Predicted band size:

57 kDa

WB Positive control:

HepG2 cells lysates treated with Anisomycin

WB Recommended dilution:

500-1000