兔抗CDC25A(Phospho-Ser178)多克隆抗體

Background:

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.

Applications:

WB

Name of antibody:

CDC25A(Phospho-Ser178)

Immunogen:

Peptide sequence around phosphorylation site of serine 178(Q-N-S(p)-A-P) derived from Human CDC25A .

Full name:

cell division cycle 25A

Synonyms：

CDC25A2

SwissProt:

P30304

WB Predicted band size:

59 kDa

WB Positive control:

A549 cells lysates treated with UV

WB Recommended dilution:

500-1000